Isaiah 51:16 (King James Bible) and I have put my words in thy mouth and I have covered thee in the shadow of mine hand
We see here the tendency for the scribe, Oliver Cowdery, to mix up the personal pronouns thy and mine. In copying from 𝓞 to 𝓟, Oliver initially wrote “thy hand”, probably under the influence of the preceding thy and thee in the verse. He caught his error, crossed out the thy and supralinearly inserted mine (and with no change in the level of ink flow). The original manuscript is extant here and reads in agreement with the King James text. For a similar error later on in this chapter, see the discussion under 2 Nephi 8:22.
Summary: In 2 Nephi 8:16, maintain “mine hand”, the reading of 𝓞; this reading also agrees with the corresponding Isaiah passage in the King James Bible.